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Literature summary extracted from
- Oxidized and Met358-->Leu mutated alpha 1-proteinase inhibitor as substrates of Pseudomonas aeruginosa elastase (1993), Biochim. Biophys. Acta, 1163, 61-66.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.26 | Pseudomonas aeruginosa | P14756 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.26 | 2-aminobenzoyl-Ala-Gly-Leu-Ala-4-nitrobenzylamide + H2O | 25°C, pH 7.4 | Pseudomonas aeruginosa | ? | - |
? |  |
| 3.4.24.26 | alpha1-proteinase inhibitor + H2O | 25°C, pH 7.4, cleavage occurs at the Pro357-Met358 bond (wild-type and recombinant Met358 inhibitor) and at the Pro357-Leu358 bond (recombinant mutant M358L inhibitor) | Pseudomonas aeruginosa | ? | - |
? | |
| 3.4.24.26 | N-chlorosuccinimide-oxidized inhibitor + H2O | 25°C, pH 7.4, cleavage occurs between Glu354 and Ala355 | Pseudomonas aeruginosa | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.24.26 | PsE | - |
Pseudomonas aeruginosa |
| 3.4.24.26 | Pseudomonas aeruginosa elastase | - |
Pseudomonas aeruginosa |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.26 | 5.8 | - |
with 2-aminobenzoyl-Ala-Gly-Leu-Ala-4-nitrobenzylamide as substrate | Pseudomonas aeruginosa |
| 3.4.24.26 | 6 | - |
with the native alpha1-proteinase inhibitor as substrate | Pseudomonas aeruginosa |
| 3.4.24.26 | 6.5 | - |
with the recombinant mutant M358L inhibitor as substrate | Pseudomonas aeruginosa |
| 3.4.24.26 | 7 | - |
with N-chlorosuccinimide-oxidized inhibitor as substrate | Pseudomonas aeruginosa |
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